Variation in lymphatic function may predispose to development of breast cancer-related lymphoedema.
Identifieur interne : 008685 ( Main/Exploration ); précédent : 008684; suivant : 008686Variation in lymphatic function may predispose to development of breast cancer-related lymphoedema.
Auteurs : S J Pain [Royaume-Uni] ; A D Purushotham ; R W Barber ; J R Ballinger ; C K Solanki ; Peter Mortimer (dermatologue) [Royaume-Uni] ; A M PetersSource :
- European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology [ 0748-7983 ] ; 2004.
Descripteurs français
- KwdFr :
- Bras (), Bras (imagerie diagnostique), Facteurs temps, Femelle, Humains, Immunoglobuline G (sang), Immunoglobulines (sang), Lymphoedème (), Lymphoedème (physiopathologie), Lymphoedème (sang), Lymphoscintigraphie, Main (), Main (imagerie diagnostique), Préparations à action retardée (métabolisme), Radiopharmaceutiques (sang), Royaume-Uni, Santé des femmes, Système lymphatique (physiologie), Technétium (sang), Tumeurs du sein (), Tumeurs du sein (physiopathologie), Tumeurs du sein (sang).
- MESH :
- imagerie diagnostique : Bras, Main.
- métabolisme : Préparations à action retardée.
- physiologie : Système lymphatique.
- physiopathologie : Lymphoedème, Tumeurs du sein.
- sang : Immunoglobuline G, Immunoglobulines, Lymphoedème, Radiopharmaceutiques, Technétium, Tumeurs du sein.
- Bras, Facteurs temps, Femelle, Humains, Lymphoedème, Lymphoscintigraphie, Main, Royaume-Uni, Santé des femmes, Tumeurs du sein.
English descriptors
- KwdEn :
- Arm (blood supply), Arm (diagnostic imaging), Breast Neoplasms (blood), Breast Neoplasms (complications), Breast Neoplasms (physiopathology), Delayed-Action Preparations (metabolism), Female, Hand (blood supply), Hand (diagnostic imaging), Humans, Immunoglobulin G (blood), Immunoglobulins (blood), Lymphatic System (physiology), Lymphedema (blood), Lymphedema (complications), Lymphedema (physiopathology), Lymphoscintigraphy, Radiopharmaceuticals (blood), Technetium (blood), Time Factors, United Kingdom, Women's Health.
- MESH :
- chemical , blood : Immunoglobulin G, Immunoglobulins, Radiopharmaceuticals, Technetium.
- chemical , metabolism : Delayed-Action Preparations.
- blood : Breast Neoplasms, Lymphedema.
- blood supply : Arm, Hand.
- complications : Breast Neoplasms, Lymphedema.
- diagnostic imaging : Arm, Hand.
- physiology : Lymphatic System.
- physiopathology : Breast Neoplasms, Lymphedema.
- Female, Humans, Lymphoscintigraphy, Time Factors, United Kingdom, Women's Health.
Abstract
Breast cancer-related lymphoedema (BCRL) remains a common complication of breast cancer treatment. Many features of this condition remain poorly understood, such as why only approximately 25% of women are affected after similar treatment, and the phenomenon of 'sparing', in which regions of an otherwise swollen arm, most commonly the hand, remain unaffected. This study uses dual-isotope lymphoscintigraphy, involving measurement of rate of clearance of radiolabelled protein from a subcutaneous depot and subsequent appearance in blood, to quantify alterations in lymphatic function in women with BCRL, and to further investigate differences between those in whom the hand is involved with swelling and those in whom it is spared.
DOI: 10.1016/j.ejso.2004.02.008
PubMed: 15135478
Affiliations:
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Le document en format XML
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<term>Breast Neoplasms (physiopathology)</term>
<term>Delayed-Action Preparations (metabolism)</term>
<term>Female</term>
<term>Hand (blood supply)</term>
<term>Hand (diagnostic imaging)</term>
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<term>Immunoglobulin G (blood)</term>
<term>Immunoglobulins (blood)</term>
<term>Lymphatic System (physiology)</term>
<term>Lymphedema (blood)</term>
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<term>Lymphedema (physiopathology)</term>
<term>Lymphoscintigraphy</term>
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<term>Immunoglobulines (sang)</term>
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<term>Lymphoedème (sang)</term>
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<term>Main ()</term>
<term>Main (imagerie diagnostique)</term>
<term>Préparations à action retardée (métabolisme)</term>
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<term>Royaume-Uni</term>
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<term>Tumeurs du sein (physiopathologie)</term>
<term>Tumeurs du sein (sang)</term>
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<front><div type="abstract" xml:lang="en">Breast cancer-related lymphoedema (BCRL) remains a common complication of breast cancer treatment. Many features of this condition remain poorly understood, such as why only approximately 25% of women are affected after similar treatment, and the phenomenon of 'sparing', in which regions of an otherwise swollen arm, most commonly the hand, remain unaffected. This study uses dual-isotope lymphoscintigraphy, involving measurement of rate of clearance of radiolabelled protein from a subcutaneous depot and subsequent appearance in blood, to quantify alterations in lymphatic function in women with BCRL, and to further investigate differences between those in whom the hand is involved with swelling and those in whom it is spared.</div>
</front>
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<name sortKey="Purushotham, A D" sort="Purushotham, A D" uniqKey="Purushotham A" first="A D" last="Purushotham">A D Purushotham</name>
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