Serveur d'exploration sur le lymphœdème

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Variation in lymphatic function may predispose to development of breast cancer-related lymphoedema.

Identifieur interne : 008685 ( Main/Exploration ); précédent : 008684; suivant : 008686

Variation in lymphatic function may predispose to development of breast cancer-related lymphoedema.

Auteurs : S J Pain [Royaume-Uni] ; A D Purushotham ; R W Barber ; J R Ballinger ; C K Solanki ; Peter Mortimer (dermatologue)‎ [Royaume-Uni] ; A M Peters

Source :

RBID : pubmed:15135478

Descripteurs français

English descriptors

Abstract

Breast cancer-related lymphoedema (BCRL) remains a common complication of breast cancer treatment. Many features of this condition remain poorly understood, such as why only approximately 25% of women are affected after similar treatment, and the phenomenon of 'sparing', in which regions of an otherwise swollen arm, most commonly the hand, remain unaffected. This study uses dual-isotope lymphoscintigraphy, involving measurement of rate of clearance of radiolabelled protein from a subcutaneous depot and subsequent appearance in blood, to quantify alterations in lymphatic function in women with BCRL, and to further investigate differences between those in whom the hand is involved with swelling and those in whom it is spared.

DOI: 10.1016/j.ejso.2004.02.008
PubMed: 15135478


Affiliations:


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Le document en format XML

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<term>Arm (blood supply)</term>
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<term>Breast Neoplasms (complications)</term>
<term>Breast Neoplasms (physiopathology)</term>
<term>Delayed-Action Preparations (metabolism)</term>
<term>Female</term>
<term>Hand (blood supply)</term>
<term>Hand (diagnostic imaging)</term>
<term>Humans</term>
<term>Immunoglobulin G (blood)</term>
<term>Immunoglobulins (blood)</term>
<term>Lymphatic System (physiology)</term>
<term>Lymphedema (blood)</term>
<term>Lymphedema (complications)</term>
<term>Lymphedema (physiopathology)</term>
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<term>Radiopharmaceuticals (blood)</term>
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<term>Time Factors</term>
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<term>Women's Health</term>
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<term>Immunoglobuline G (sang)</term>
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<term>Lymphoedème (sang)</term>
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<term>Main (imagerie diagnostique)</term>
<term>Préparations à action retardée (métabolisme)</term>
<term>Radiopharmaceutiques (sang)</term>
<term>Royaume-Uni</term>
<term>Santé des femmes</term>
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<div type="abstract" xml:lang="en">Breast cancer-related lymphoedema (BCRL) remains a common complication of breast cancer treatment. Many features of this condition remain poorly understood, such as why only approximately 25% of women are affected after similar treatment, and the phenomenon of 'sparing', in which regions of an otherwise swollen arm, most commonly the hand, remain unaffected. This study uses dual-isotope lymphoscintigraphy, involving measurement of rate of clearance of radiolabelled protein from a subcutaneous depot and subsequent appearance in blood, to quantify alterations in lymphatic function in women with BCRL, and to further investigate differences between those in whom the hand is involved with swelling and those in whom it is spared.</div>
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